Skip to Main Content

EndNote 21

EndNote 21 essential information

What is EndNote?


What can EndNote do for you?

  • Collect and organize of references
  • Attach, read, and annotate PDFs 
  • Insert citations and bibliography in your paper
  • Share references with colleagues to collaborate

What's new in EndNote 21?

  • Organize references with customized tags and labels
  • Exclusive EndNote Web interface
  • Cite While You Write with Google Docs
  • Share and collaborate with up to 1000 colleagues

Who Can Download and Install EndNote?

  • Current students, staff, and faculty of University of Kansas Medical Center
  • Dually employed, i.e., (appointed/employed in both hospital and university) staff.

University licensing of EndNote software through Dykes Library does not include University of Kansas Health System employees unless they have dual appointments.

EndNote for UKHS employees

Call Hospital IT at 913-945-9999 and Press 1, or submit a ticket to UKHS MyIT service 

  • Request Service
  • Software request
  • Fill out the form and submit the request.

Dually employed (Hospital and University) persons can install EndNote through University license on their university computers and personal computers as well. Follow installation instructions 

Download & Install EndNote X 21 ( Windows & MacOS)

Close all Microsoft products, especially MS Word that is running on your computer before you start downloading

  For your personal computers:

  1. Download EndNote for your personal computers from MyKUMC software page
  2. Authenticate with your KUMC username and password in the myKUMC software page  
  3. Scroll down to see EndNote 21
  4. Select the EndNote for your computer i.e MacOS vs. Windows


Important : The Endnote download for Windows is a Zipped or compressed file. After downloading you must double click and extract  the file by right clicking. 

  1. EndNote folder file will download
  2. Right click and select Extract All
  3. The files will be extracted to a selected folder such as your desktop or documents.
  4. Double click the file named EN21inst.msi to start installation.
  5. Click next and follow the prompts to EndNote setup
  6. Agree licensing prompts to Finish installation.


  1. EndNote X 21 Installer.dmg file will download
  2. Click save (on your desktop or documents)
  3. Open Install EndNote X 21 App from the prompt. You can also drag and drop the dmg file to the  Applications folder to install.
  4. Agree licensing terms and follow the prompts to complete installation.

  For University supplied computers:

Are you encountering issues with downloading EndNote X 21? Contact KUMC IT Customer Support at Phone: 913-945-9999, option 2 or open a ticket

You may Uninstall the previous versions of EndNote that is running in your computer in-order to save space and better organize

Uninstall previous versions of EndNote (X9 or X20)

Is EndNote X9 or X20 still running on your computer?

It is suggested that you uninstall any previous versions before or after installing EndNote 21.


  1. Open the Control Panel.
  2. Windows XP: Click on Add/Remove Programs.
  3. Windows Vista/7/8/10: Click on Programs > Programs and Features. 
  4. Choose "EndNote XX” (where XX is the version) from the list and click on Uninstall.


  1. Open the EndNote program.
  2. Click on the EndNote menu and select the Customizer.
  3. Click the Uninstall option at the bottom of this menu. When this is complete, it will remove all external components.
  4. Click Quit.
  5. Drag the EndNote folder from the Applications folder to the Trash.
  6. Empty the Trash.

Uninstalling the previous versions of EndNote may not effect your EndNote library. You can also make a backup copy of your current EndNote library using the following commands.

  • File > Compressed Library for libraries smaller than 5GB
  • File > Save a Copy for larger libraries